| Identification | Back Directory | [Name]
Rofleponide | [CAS]
144459-70-1 | [Synonyms]
Rofleponide
Unii-R9iq7gvl3e
Rofleponide [inn]
Pregn-4-ene-3,20-dione, 16,17-[(1R)-butylidenebis(oxy)]-6,9-difluoro-11,21-dihydroxy-, (6α,11β,16α)- | [Molecular Formula]
C25H34F2O6 | [MDL Number]
MFCD00914391 | [MOL File]
144459-70-1.mol | [Molecular Weight]
468.534 |
| Hazard Information | Back Directory | [Uses]
Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models[1]. | [References]
[1] Thalén A, et al. Synthesis and structure elucidation of potential 6-oxygenated metabolites of (22R)-6α, 9α-difluoro-11β, 21-dihydroxy-16α, 17α-propylmethylenedioxypregn-4-ene-3, 20-dione, and related glucocorticosteroids[J]. Steroids, 2000, 65(1): 16-23. DOI:10.1016/s0039-128x(99)00080-x |
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