| Identification | More | [Name]
Trityl olmesartan | [CAS]
144690-92-6 | [Synonyms]
4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1h-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
Trityl olmesartan
TRITYL OLMESARTAN MEDOXOMIL
TRIPHENYL METHYL OLMESARTAN
1H-Imidazole-5-carboxylic acid,4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
Tritylolmesartan(ForOlmesartan)
TRITYL OLMESARTAN MEDOXOMIL (99.5%)
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
N-Triphenyl Methyl Omesartan | [EINECS(EC#)]
604-437-3 | [Molecular Formula]
C48H44N6O6 | [MDL Number]
MFCD09954745 | [Molecular Weight]
800.9 | [MOL File]
144690-92-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White to White Powder | [Melting point ]
104-106°C | [Boiling point ]
960.0±75.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMF: 1 mg/ml,DMSO: 1 mg/ml | [form ]
A solid | [pka]
13.21±0.29(Predicted) | [Usage]
Olmesartan medoxomil analog as angiotensin II antagonist. | [InChIKey]
IJOPLMOXIPGJIJ-UHFFFAOYSA-N | [SMILES]
C1(CCC)N(CC2=CC=C(C3=CC=CC=C3C3N(C(C4=CC=CC=C4)(C4=CC=CC=C4)C4=CC=CC=C4)N=NN=3)C=C2)C(C(OCC2=C(C)OC(=O)O2)=O)=C(C(O)(C)C)N=1 | [CAS DataBase Reference]
144690-92-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to White Powder | [Uses]
Olmesartan medoxomil analog as angiotensin II antagonist. | [Uses]
Olmesartan medoxomil intermediate. | [Synthesis]
This describes steps for preparing a trityl-protected intermediate in olmesartan medoxomil synthesis:
1. An imidazole ester derivative is alkylated with a trityl-protected biphenyltetrazole bromide in acetone with K₂CO₃/phase-transfer catalyst. Work-up |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Valiant Co., Ltd.
|
| Telephone: |
0535-6101880 |
| Website: |
http://www.valiant-cn.com/ |
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