ChemicalBook--->CAS DataBase List--->1448451-72-6

1448451-72-6

Request For Quotation
1448451-72-6 Structure

1448451-72-6 Structure
IdentificationBack Directory
[Name]

Azido-PEG5-CH2CO2t-butyl ester
[CAS]

1448451-72-6
[Synonyms]

Azido-PEG5-Boc
N3-PEG5-CH2COOtBu
Reaxys ID: 23811246
AZIDO-PEG5-CH2CO2TBU
Azido-PEG5-CH2CO2t-butyl ester
[Molecular Formula]

C16H31N3O7
[MDL Number]

MFCD27977490
[MOL File]

1448451-72-6.mol
[Molecular Weight]

377.44
Chemical PropertiesBack Directory
[storage temp. ]

Store at 0-8 °C
Hazard InformationBack Directory
[Description]

Azido-PEG5-CH2CO2-t-Bu consist of an azide group(N3) and a t-butyl ester.The azide group can react with alkyne, BCN, DBCO via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG spacer increases solubility in aqueous media.
[Uses]

Azido-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1448451-72-6 suppliers list
Company Name: Hunan HuaTeng Pharmaceutical Co., Ltd.,  
Telephone: 400-8592883 15367835770
Website: www.huatengsci.com
Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
Telephone: 0431-80534353 19917294565
Website: http://www.chemextension.com
Company Name: Jinan elephant international trading co., LTD  
Telephone:
Website: www.chemicalbook.com/ShowSupplierProductsList19883/0_EN.htm
Company Name: Amatek Scientific Co. Ltd.  
Telephone: 0512-56316828 400-867-5858;400-867-5858
Website: http://www.amateksci.com
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Telephone: +86-156-80926068 +86-15680926068
Website: http://www.confluore.cn/
Company Name: Shandong utilizing biological technology co., LTD  
Telephone: 18669728830 15966937598
Website: www.demaichem.com
Company Name: Alpha Biopharmaceuticals Co., Ltd  
Telephone: 0411-39042497
Website: alphabiopharm.com/?reqp=1&reqr=
Company Name: Nextpeptide Inc  
Telephone: +86-0571-81612335 +8613336028439
Website: http://www.nextpeptide.com/
Company Name: Shaanxi Xinyan Bomei Biotechnology Co., Ltd.  
Telephone: 13892832556
Website: www.xinyanbm.com/
Company Name: Xiamen Sinopeg Biotech Co., Ltd.  
Telephone: 400-9189898 17359873007
Website: http://www.sinopeg.com.cn
Company Name: Chongqing Chemdad Co., Ltd  
Telephone: +86-023-6139-8061 +86-86-13650506873
Website: http://www.chemdad.com/
Company Name: Zhengzhou Convergence Chemical Co. LTD  
Telephone: 13393710386
Website: www.chemicalbook.com/supplier/23627897/
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Telephone: 025-85563444 18351873721
Website: http://www.synzest.com
Company Name: Zhengzhou Akem Chemical Co., Ltd  
Telephone: 13303867194
Website: www.acmechem.cn/
Company Name: Xi'an Qiyue Biotechnology Co., Ltd.  
Telephone: 400-400-6966-012-012 17778955912
Website: http://www.qiyuebio.com/
Company Name: Affinity（Wuhan）Ltd.  
Telephone: 15841022315
Website: https://precisepeg.com
Company Name: Jinan Demai Medical Technology Co., LTD  
Telephone: 18669728830 15806766175
Website: https://www.demaichem.com/
Company Name: Shandong Dayou Pharmaceutical Research and Development Co., Ltd.  
Telephone: dayouchem@126.com 15165037910
Website:
Tags:1448451-72-6 Related Product Information
217180-81-9 864681-04-9 172531-36-1 251564-45-1 1984776-39-7 252881-73-5