| Identification | Back Directory | [Name]
4-PREGNEN-20-ALPHA-OL-3-ONE | [CAS]
145-14-2 | [Synonyms]
C04042
20α-OH-P
NSC 68630
20α-Progerol
Progesterol-20α
20-alpha-progerol
dihydroprogesterone
20α-OH-Progesterone
progesterol-20-alpha
Progesterone EP IMP B
(20s)-pregn-4-en-3-on
4-pregnen-20A-ol-3-one
4-Pregnen-20α-ol-3-one
4-Pregnen-3-one-20α-ol
20α-Dihydroprogesterone
Δ4-Pregnen-20α-ol-3-one
Pregn-4-ene-20α-ol-3-one
Δ4-Pregnene-20α-ol-3-one
4-PREGNEN-20ALPHA-OL-3-ON
20(s)-hydroxyprogesterone
Progesterone EP Impurity B
20a-Hydroxypregn-4-en-3-one
20α-Hydroxy-4-pregnen-3-one
4-PREGNEN-20-ALPHA-OL-3-ONE
20-ALPHA-DIHYDROPROGESTERONE
20-ALPHA-HYDROXYPROGESTERONE
20α-Hydroxy-Δ4-pregnen-3-one
20α-Hydroxydihydroprogesterone
20alpha-Hydroxypregn-4-en-3-one
20-alpha-hydroxy-pregn-4-en-3-on
20-ALPHA-HYDROXY-4-PREGNEN-3-ONE
(20s)-20-hydroxypregn-4-en-3-one
20-alpha-hydroxydihydroprogesterone
Pregn-4-en-3-one, 20-hydroxy-, (20S)-
Progesterone Impurity 2(Progesterone EP Impurity B)
20α-Hydroxy-4-pregnen-3-one, 20α-Hydroxyprogesterone
Progesterone EP Impurity B (20(S)-Hydroxy Progesterone)
(8S,9S,10R,13R,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
(8S,9S,10R,13S,14S,17S)-17-((S)-1-hydroxyethyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one | [EINECS(EC#)]
205-649-5 | [Molecular Formula]
C21H32O2 | [MDL Number]
MFCD00009823 | [MOL File]
145-14-2.mol | [Molecular Weight]
316.48 |
| Chemical Properties | Back Directory | [Melting point ]
171-172 °C | [Boiling point ]
451.7±14.0 °C(Predicted) | [density ]
1.13 g/cm3 | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
15.05±0.20(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16-,17+,18-,19-,20-,21+/m0/s1 | [InChIKey]
RWBRUCCWZPSBFC-RXRZZTMXSA-N | [SMILES]
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H]([C@@H](O)C)CC3)CC2 |
| Hazard Information | Back Directory | [Uses]
Δ4-Pregnen-20α-ol-3-one (Progesterone EP Impurity B) is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites. | [Uses]
Δ4-Pregnen-20α-ol-3-one is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites. | [Definition]
ChEBI: (20S)-20-hydroxypregn-4-en-3-one is a 20-hydroxypregn-4-en-3-one. It has a role as a human metabolite and a mouse metabolite. |
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