Identification | Back Directory | [Name]
(3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid | [CAS]
1454575-38-2 | [Synonyms]
ZM 522 (3β)-3-[(4-Fluorobenzoyl)oxy]lup-20(29)-en-28-oic acid | [Molecular Formula]
C37H51FO4 | [MOL File]
1454575-38-2.mol | [Molecular Weight]
578.8 |
Hazard Information | Back Directory | [Uses]
ZM522 is a CD73 inhibitor with an IC50 value of 0.56 μM. ZM522 effectively increases the levels of interferon-γ (INF-γ) and enhances immune activity by regulating the activation status of T cells. ZM522 holds promise for research in the fields of immunology and cancer therapy[1]. | [References]
[1] Zhang Y, et al. Application of a fluorine strategy in the lead optimization of betulinic acid to the discovery of potent CD73 inhibitors. Steroids. 2022 Dec;188:109112. DOI:10.1016/j.steroids.2022.109112 |
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