ChemicalBook--->CAS DataBase List--->145599-86-6

145599-86-6

145599-86-6 Structure

145599-86-6 Structure
IdentificationMore
[Name]

CERIVASTATIN SODIUM
[CAS]

145599-86-6
[Synonyms]

BAYCOL
CERIVASTATIN NA
CERIVASTATIN SODIUM
CERIVASTATIN, SODIUM SALT
LIPOBAY
RIVASTATIN
sodium 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-dipropan-2-yl-pyrid in-3-yl]-3,5-dihydroxy-hept-6-enoate
7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-dipropan-2-yl-pyrid in-3-yl]-3,5-dihydroxy-hept-6-enoate
(3R,5S,6E)-7-[4-(p-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl]-3,5-dihydroxy-6-heptenoic acid
6-Heptenoic acid, 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-, (3R,5S,6E)-
6-Heptenoic acid, 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-, [S-[R*,S*-(E)]]-
[Molecular Formula]

C26H33FNNaO5
[MDL Number]

MFCD07787637
[Molecular Weight]

481.53
[MOL File]

145599-86-6.mol
Chemical PropertiesBack Directory
[Melting point ]

>176oC (dec.)
[Boiling point ]

646.3±55.0 °C(Predicted)
[density ]

1.181±0.06 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under Inert Atmosphere
[solubility ]

Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

Solid
[pka]

pKa 4.38 (H2O t=25 I=0.025) (Uncertain);5.29(H2O t=25 I=0.025) (Uncertain)
[color ]

White to Off-White
[Stability:]

Hygroscopic
[CAS DataBase Reference]

145599-86-6(CAS DataBase Reference)
[EPA Substance Registry System]

6-Heptenoic acid, 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1- methylethyl)-3-pyridinyl]-3,5-dihydroxy-, (3R,5S,6E)- (145599-86-6)
Safety DataBack Directory
[Hazardous Substances Data]

145599-86-6(Hazardous Substances Data)
Hazard InformationBack Directory
[Uses]

assimilate cholesterol
[Definition]

ChEBI: (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cho esterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.
[Brand name]

Baycol (Bayer);Cholstat.
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