| Identification | Back Directory | [Name]
3,8,10-Trihydroxy-6-(2-methyl-1-propenyl)-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-7-one | [CAS]
145643-96-5 | [Synonyms]
Cyclocommunol
3,8,10-trihydroxy-6-(2-methylprop-1-enyl)-6H-chromeno[4,3-b]chromen-7-one
3,8,10-Trihydroxy-6-(2-methyl-1-propenyl)-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-7-one
6H,7H-[1]Benzopyrano[4,3-b][1]benzopyran-7-one, 3,8,10-trihydroxy-6-(2-methyl-1-propenyl)- | [Molecular Formula]
C20H16O6 | [MDL Number]
MFCD20731040 | [MOL File]
145643-96-5.mol | [Molecular Weight]
352.34 |
| Chemical Properties | Back Directory | [Boiling point ]
628.2±55.0 °C(Predicted) | [density ]
1.53±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
cryst. | [pka]
6.95±0.40(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Cyclocommunol is a prenylflavonoid with antityrosinase and antiplatelet activitie, can be solated from breadfruit. Cyclocommunol exerts anti-tumor activity and inhibits the growth of human hepatoma and gastric cancer cells with IC50 values between 16 and 80 μM. Cyclocommunol shows proapoptotic effect on oral squamous cell carcinoma (OSCC)[1]. | [Definition]
ChEBI: Cyclocommunol is an extended flavonoid. | [target]
PAFR | [References]
[1] Weng JR, et al. Cyclocommunol induces apoptosis in human oral squamous cell carcinoma partially through a Mcl-1-dependent mechanism. Phytomedicine. 2018 Jan 15;39:25-32. DOI:10.1016/j.phymed.2017.12.004 |
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