ChemicalBook--->CAS DataBase List--->145808-47-5

145808-47-5

Request For Quotation
145808-47-5 Structure

145808-47-5 Structure
IdentificationBack Directory
[Name]

MARGATOXIN
[CAS]

145808-47-5
[Synonyms]

MGTX
RMGTX
MARGATOXIN
RMARGATOXIN
MGTX (SCORPION)
MARGATOXIN (MGTX)
BARK SCORPION VENOM
MARGATOXIN (SCORPION)
MARGATOXIN, RECOMBINANT
SCORPION VENOM CENTRUROIDES SCULPTURATUS
MARGATOXIN SCORPION, CENTRUROIDES*MARGAR ITATUS
margatoxin from centruroides margaritatus (scorpion)
MARGATOXIN >97%PURITY \ SPECIFIC K(V)1.3 CHANNEL K+CHANNEL BLOCKER
THR-ILE-ILE-ASN-VAL-LYS-CYS-THR-SER-PRO-LYS-GLN-CYS-LEU-PRO-PRO-CYS-LYS-ALA-GLN-PHE-GLY-GLN-SER-ALA-GLY-ALA-LYS-CYS-MET-ASN-GLY-LYS-CYS-LYS-CYS-TYR-PRO-HIS
H-THR-ILE-ILE-ASN-VAL-LYS-CYS-THR-SER-PRO-LYS-GLN-CYS-LEU-PRO-PRO-CYS-LYS-ALA-GLN-PHE-GLY-GLN-SER-ALA-GLY-ALA-LYS-CYS-MET-ASN-GLY-LYS-CYS-LYS-CYS-TYR PRO-HIS-OH
H-Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His-OH
[Molecular Formula]

C178H286N52O50S7
[MDL Number]

MFCD00132225
[MOL File]

145808-47-5.mol
[Molecular Weight]

4178.95
Questions And AnswerBack Directory
[Uses]

Margatoxin is a highly pure, synthetic, and biologically active peptide toxin.
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

Powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 0.50 mg/ml in water
[Sequence]

Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His (Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys36)
[InChIKey]

OVJBOPBBHWOWJI-UHFFFAOYSA-N
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H312-H332
[Precautionary statements ]

P261-P280h-P301+P312a-P304+P340-P321-P501a
[Safety Statements ]

22
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Biochem/physiol Actions]

Margatoxin is an α-KTx toxin, which is majorly used in ion channel research. It is a 39-amino acid peptide, which is a specific K(V)1.3 channel voltage-dependent K+ channel blocker. Margatoxin is an immunosuppressant that is isolated from the venom of the scorpion Centruroides margaritatus.
[in vivo]

Margatoxin (i.p.; 1 pmol/g) significantly decreases thiogycollate-induced leukocyte transmigration in the peritoneal cavity in 12-week-old C57BL6/J mice[2].

[storage]

-20°C
145808-47-5 suppliers list
Company Name: GL Biochem (Shanghai) Ltd  
Telephone: 21-61263452 13641803416
Website: http://www.glschina.com/
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Telephone: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Chemsky (shanghai) International Co.,Ltd  
Telephone: 021-50135380
Website: www.shchemsky.com
Company Name: Hunan Hui Bai Shi Biotechnology Co., Ltd.  
Telephone: 0731-85526065 13308475853
Website: http://www.hnhbsj.com/
Company Name: Sigma-Aldrich  
Telephone: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: Nanjing Leon Biological Technology Co., Ltd.  
Telephone: 025-84523390 -127; 17705183659
Website: http://www.njleonbiotech.com
Company Name: Nanjing Peptide Biotech Ltd.  
Telephone: 025-58361106-805 15951641583
Website: http://www.njpeptide.com
Company Name: Hangzhou Peptidego Biotech Co.,Ltd.  
Telephone: 0571-87213919 15967184799
Website: peptidego.com
Company Name: Shanghai Jizhi Biochemical Technology Co. Ltd.  
Telephone: 021-4009004166/18616739031 18616739031
Website: www.acmec-e.com/
Company Name: Nanjing Meihao Pharmaceutical Technology Co., Ltd.  
Telephone: meitaochem@126.com
Website: www.chemicalbook.com/ShowSupplierProductsList31244/0_EN.htm
Company Name: Zhejiang J&C Biological Technology Co.,Limited  
Telephone: +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: Chengdu Peter-like Biotechnology Co., Ltd.  
Telephone: 18108052721
Website: https://www.weikeqi-biotech.com/
Company Name: Nanjing chengqimei Biotechnology Co., Ltd  
Telephone: 19850819832
Website: www.chemicalbook.com/ShowSupplierProductsList398701/0_EN.htm
Company Name: Nanchang Tianzhen Biotechnology Co., Ltd  
Telephone: 13758194781 13173652190
Website: www.tanzhenbio.com
Company Name: Wuxi Helen Biotechnology Co., Ltd.,  
Telephone: 0510-85629785 18013409632
Website: http://www.reading-chemicals.com
Company Name: Nanjing TGpeptide Biotechnology Co.,Ltd.  
Telephone: 18115476705
Website: http://www.tgpeptide.com/Index.aspx
Company Name: Hangzhou Go Top Peptide Biotech  
Telephone: 0571-88211921 18157160918
Website: www.gotopbio.com/
Company Name: Energy Chemical  
Telephone: 400-0056266
Website: www.energy-chemical.com
Tags:145808-47-5 Related Product Information
2769-64-4 39687-95-1 14542-93-9 7188-38-7 645-96-5 36635-61-7 2999-46-4