| Identification | More | [Name]
3-(TRIFLUOROACETYL)INDOLE | [CAS]
14618-45-2 | [Synonyms]
2,2,2-TRIFLUORO-1-(1H-INDOL-3-YL)-1-ETHANONE
3-(TRIFLUOROACETYL)INDOLE
3-(TRIFLUOROACETYL)INDOLE 99% | [Molecular Formula]
C10H6F3NO | [MDL Number]
MFCD00182114 | [Molecular Weight]
213.16 | [MOL File]
14618-45-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT |
| Hazard Information | Back Directory | [Uses]
- Reactant for enantioselective synthesis of indoles via palladium-catalyzed kinetic asymmetrical alkylation
- Reactant for preparation of N-pyridinyl indolecarboxamides via amidation of aminopyridine derivatives. with indolecarboxylic acid
- Reactant for preparation of mast cell tryptase inhibitors, starting from indoles; using amidation as the key step
- Reactant for formation of Michael adducts via Baylis-Hillman reaction
- Reactant for preparation of indolecarboxamides via haloform cleavage of (trifluoroacetyl)indole with lithium dialkylamides
| [Uses]
Reactant for enantioselective synthesis of indoles via palladium-catalyzed kinetic asymmetrical alkylation. Reactant for preparation of N-pyridinyl indolecarboxamides via amidation of aminopyridine derivatives. with indolecarboxylic acid 2 Reactant for preparation of mast cell tryptase inhibitors, starting from indoles; using amidation as the key step 3 Reactant for formation of Michael adducts via Baylis-Hillman reaction 4 Reactant for preparation of indolecarboxamides via haloform cleavage of (trifluoroacetyl)indole with lithium dialkylamides. | [General Description]
3-(Trifluoroacetyl)indole is a heterocyclic trifluoromethyl ketone. One of the methods reported for its synthesis is by the reaction of indole with trifluoroacetic anhydride. |
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