| Identification | Back Directory | [Name]
FR901463 | [CAS]
146478-74-2 | [Synonyms]
FR901463
F 901463
WB 2663A
RONUKPQOBQKEHX-QHYZBLTGSA-N | [Molecular Formula]
C27H42ClNO8 | [MDL Number]
MFCD28347813 | [MOL File]
146478-74-2.mol | [Molecular Weight]
544.077 |
| Hazard Information | Back Directory | [Uses]
FR901463 is a potent anti-cancer agent and can be used for cancer research. FR901463 enhances the transcriptional activity of the promoter of SV40 DNA virus[1]. | [Definition]
ChEBI: A cyclic hemiketal isolated from the fermentation broth of Pseudomonas sp.no.2663. It displays potent cytotoxic activity against human tumour cells. | [References]
[1] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1996 Dec;49(12):1196-203. DOI:10.7164/antibiotics.49.1196 |
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