| Identification | Back Directory | [Name]
S 2720 | [CAS]
146739-86-8 | [Synonyms]
S 2720
prop-1-en-2-yl 7-chloro-2,2-dimethyl-3-sulfanylidene-4H-quinoxaline-1-carboxylate | [Molecular Formula]
C14H15ClN2O2S | [MDL Number]
MFCD00922640 | [MOL File]
146739-86-8.mol | [Molecular Weight]
310.799 |
| Hazard Information | Back Directory | [Description]
S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline. | [Uses]
S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection[1]. | [References]
[1] Kleim JP, et al. Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication. Antimicrob Agents Chemother. 1993 Aug;37(8):1659-64. DOI:10.1128/AAC.37.8.1659 |
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