ChemicalBook--->CAS DataBase List--->147127-19-3

147127-19-3

147127-19-3 Structure

147127-19-3 Structure
IdentificationBack Directory
[Name]

(S)-Tenofovir
[CAS]

147127-19-3
[Synonyms]

(S)-TDF
(S)-PMPA
(S)-GS 1278
(S)-Tenofovir
TAF Impurity L
Tenofovir alafenamide-23
Tenofovir Disoproxil Impurity 26
(S)-9-(2-Phosphonomethoxypropyl)adenine
[(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
(S)-(1-(6-aMino-9H-purin-9-yl)propan-2-yloxy)Methylphosphonic acid
(S)-[[[1-(6-Amino-9H-purin-9-yl)-2-propyl]oxy]methyl]phosphonic Acid
3-O-BENZYL-4-(HYDROXYMETHYL-1,2-O-ISOPROPYLIDENE)--D-ERYTHROPENTOFURANOSE
Phosphonic acid,P-[[(1S)-2-(6-aMino -9H-purin-9-yl)-1-Methylethoxy]Methyl]-
Tenofovir impurity 45/(S)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C9H14N5O4P
[MDL Number]

MFCD21604708
[MOL File]

147127-19-3.mol
[Molecular Weight]

287.21
Chemical PropertiesBack Directory
[Melting point ]

>260°C (dec.)
[Boiling point ]

616.1±65.0 °C(Predicted)
[density ]

1.79±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

DMSO (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

Solid
[pka]

2.36±0.10(Predicted)
[color ]

White to Off-White
[InChI]

InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1
[InChIKey]

SGOIRFVFHAKUTI-LURJTMIESA-N
[SMILES]

P(CO[C@@H](C)CN1C2C(N=C1)=C(N)N=CN=2)(=O)(O)O
Hazard InformationBack Directory
[Uses]

(S)-Tenofovir is an S-enatiomeric derivative of Tenofovir (T018500). (S)-Tenofovir displays virucidal activity against herpes, visna virus and retrovirus. The S enantiomer of Tenofovir (T018500) is less effective against HIV than their (R)-enantiomeric counterparts.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

(S)-Tenofovir(147127-19-3)1HNMR
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