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147325-09-5

147325-09-5 Structure

147325-09-5 Structure
IdentificationBack Directory
[Name]

(S)-N-Boc-L-homoserine Ethyl Ester
[CAS]

147325-09-5
[Synonyms]

(S)-N-Boc-L-homoserine Ethyl Ester
REF DUPL: N-BOC-L-HOMOSERINE METHYL ESTER
N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine Ethyl Ester
(S)-methyl 2-(tert-butoxycarbonylamino)-4-hydroxybutanoate
[Molecular Formula]

C11H21NO5
[MDL Number]

MFCD18207790
[MOL File]

147325-09-5.mol
[Molecular Weight]

247.29
Chemical PropertiesBack Directory
[Appearance]

Off-White to Pale Yellow
[Melting point ]

54-56°C
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Pale Yellow
Hazard InformationBack Directory
[Chemical Properties]

Off-White to Pale Yellow
[Uses]

Amino acid derivative useful for the treatment of Alzheimer disease.
[Uses]

Amino acid derivative useful for the treatment of Alzheimer's disease.
[Description]

(S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.
[References]

[1] JACOB M. JANEY. Raney-Co Mediated Reductive Cyclization of an α,β-Unsaturated Nitrile[J]. The Journal of Organic Chemistry, 2008, 73 8: 3212-3217. DOI: 10.1021/jo8000996
[2] MASAYASU KUWAHARA  Masahiko S ?  Miki Arimitsu. Synthesis of δ-amino acids with an ether linkage in the main chain and nucleobases on the side chain as monomer units for oxy-peptide nucleic acids[J]. Tetrahedron, 1999, 55 33: Pages 10067-10078. DOI: 10.1016/s0040-4020(99)00541-4
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