ChemicalBook--->CAS DataBase List--->1474022-02-0

1474022-02-0

Request For Quotation
1474022-02-0 Structure

1474022-02-0 Structure
IdentificationBack Directory
[Name]

Urea, N-[1-(3-cyanophenyl)-3-(1,1-dimethylethyl)-1H-pyrazol-5-yl]-N'-[3-methyl-4-(4-pyridinyloxy)phenyl]-
[CAS]

1474022-02-0
[Synonyms]

PF 05381941,PF05381941
Urea, N-[1-(3-cyanophenyl)-3-(1,1-dimethylethyl)-1H-pyrazol-5-yl]-N'-[3-methyl-4-(4-pyridinyloxy)phenyl]-
[Molecular Formula]

C27 H26 N6 O2
[MDL Number]

MFCD34578211
[MOL File]

1474022-02-0.mol
[Molecular Weight]

466.53
Chemical PropertiesBack Directory
[Boiling point ]

561.0±50.0 °C(Predicted)
[density ]

1.21±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 100 mg/mL (214.35 mM; Need ultrasonic)
[form ]

Solid
[pka]

13.37±0.70(Predicted)
[color ]

Off-white to brown
Hazard InformationBack Directory
[Uses]

PF-05381941 is a potent dual inhibitor of TAK1/p38α, with IC50s of 156 and186 nM, respectively[1].
[IC 50]

p38α: 186 nM (IC50); TAK1: 156 nM (IC50)
[storage]

Store at -20°C
[References]

[1] Kilty I, et al. TAK1 inhibition in the DFG-out conformation. Chem Biol Drug Des. 2013;82(5):500-505. DOI:10.1111/cbdd.12169
Spectrum DetailBack Directory
[Spectrum Detail]

Urea, N-[1-(3-cyanophenyl)-3-(1,1-dimethylethyl)-1H-pyrazol-5-yl]-N'-[3-methyl-4-(4-pyridinyloxy)phenyl]-(1474022-02-0)1HNMR
1474022-02-0 suppliers list
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226 , 13588875226
Website: www.hzclap.com/en
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Tel: +86-18341751992 +86-15382112998 , +86-15382112998
Website:
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel: +8613720134139 , +8613720134139
Website: http://www.jknbiochem.com/
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Website: http://www.bioll.com
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Website: www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 021-61312847; 18021002903
Website: http://www.shyuanye.com
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Tel: 010-50973130 18101056239
Website: www.solarbio.com
Company Name: ShangHai ChuanQian Chemcial Technique Centre  
Tel: 15869524721
Website: www.chemicalbook.com/ShowSupplierProductsList68594/0_EN.htm
Company Name: cjbscvictory  
Tel: 13348960310 13348960310;
Website: https://www.weikeqi-biotech.com/
Company Name: Wuhan Augda Biotechnology Co., Ltd  
Tel: 15071299552
Website: https://www.chemicalbook.com/supplier/24275232/1.htm
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd  
Tel: 024-024-024-88590548 18341751992
Website:
Company Name: Wuhan Jingkangen Biomedical Technology Co., Ltd  
Tel: 13720134139 086-15871494362 13720134139
Website: https://www.jknbiochem.com
Company Name: Shandong Mopai Biotechnology Co., Ltd  
Tel: 13053322091
Website: www.chemicalbook.com/showsupplierproductslist1804467/0_en.htm
Company Name: Changsha Fuzhen Biotechnology Co.，LTD  
Tel: 18229892877 13823398779
Website: www.chemicalbook.com/supplier/25777903/
Tags:1474022-02-0 Related Product Information