| Identification | Back Directory | [Name]
H-CYS-TYR-ALA-ALA-PRO-LEU-LYS-PRO-ALA-LYS-SER-CYS-OH | [CAS]
147819-32-7 | [Synonyms]
JB1
H 1356
IGF-I ANALOG
IGF-I Analog
JB1
JB1 trifluoroacetate salt
JB-1 trifluoroacetate salt
INSULIN-LIKE GROWTH FACTOR ANALOG
CYS-TYR-ALA-ALA-PRO-LEU-LYS-PRO-ALA-LYS-SER-CYS
H-CYS-TYR-ALA-ALA-PRO-LEU-LYS-PRO-ALA-LYS-SER-CYS-OH
H-Cys-Tyr-Ala-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Cys-OH (Disulfide bond)
H-Cys-Tyr-Ala-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Cys-OH trifluoroacetate salt
L-Cysteine, L-cysteinyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-leucyl-L-lysyl-L-prolyl-L-alanyl-L-lysyl-L-seryl-, cyclic (1→12)-disulfide
L-Cysteinyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-leucyl-L-lysyl-L-prolyl-L-alanyl-L-lysyl-L-seryl-L-Cysteine, cyclic (1-12)-disulfide trifluoroacetate salt | [Molecular Formula]
C55H88N14O15S2 | [MDL Number]
MFCD00237120 | [MOL File]
147819-32-7.mol | [Molecular Weight]
1249.5 |
| Chemical Properties | Back Directory | [Boiling point ]
1615.0±65.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
film | [pka]
2.94±0.70(Predicted) | [InChIKey]
MPUVBZQBFGGAAS-XHGDPFBQSA-N |
| Hazard Information | Back Directory | [Biological Activity]
JB1 is an IGF-I peptide analog; IGF-1 receptor antagonist. IGF-1once known as somatomedin Cis involved in a multitude of activites including promoting growth and developmentparticularly neural developmentand involved in the growth and proliferation in a variety of human cancers. JB1 is a 12-amino acid cyclic peptidean IGF-1 analogused by researchers in a variety of fields to inhibit IGF activity by inhibiting binding of IGF-1 to its receptor. |
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