| Identification | Back Directory | [Name]
tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH | [CAS]
148182-34-7 | [Synonyms]
tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH
L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl]-L-leucyl]-D-phenylalanyl]-L-leucyl]- (9CI) | [Molecular Formula]
C44H59N5O8 | [MDL Number]
MFCD00076350 | [MOL File]
148182-34-7.mol | [Molecular Weight]
785.97 |
| Chemical Properties | Back Directory | [Boiling point ]
1043.2±65.0 °C(Predicted) | [density ]
1.167±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.51±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Boc-Phe-Leu-Phe-Leu-Phe-OH |
| Hazard Information | Back Directory | [Uses]
Boc-FLFLF is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin[1][2]. | [References]
[1] Schepetkin IA, et al. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochem Pharmacol. 2014 Dec 15;92(4):627-41. DOI:10.1016/j.bcp.2014.09.027
[2] Pei L, et al. Annexin 1 exerts anti-nociceptive effects after peripheral inflammatory pain through formyl-peptide-receptor-like 1 in rat dorsal root ganglion. Br J Anaesth. 2011 Dec;107(6):948-58. DOI:10.1093/bja/aer299 |
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Combio (Suzhou) Ltd.
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17751201929; 17751201929 |
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http://www.combiosz.com/ |
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