| Identification | Back Directory | [Name]
11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE | [CAS]
1482-50-4 | [Synonyms]
dihydrocortisol
5B-Dihydrocortisol
52-Dihydrocortisol
5β-Dihydrocortisol
5-BETA-DIHYDROCORTISOL
21-Di[methylenebis(oxy)] 5&alpha
5β-Pregnane-11β,17α,21-triol-3,20-dione
5B-pregnane-11B-17A-21-triol-3-20-dione
5-BETA-PREGNAN-11-BETA, 17,21-TRIOL-3,20-DIONE
5BETA-PREGNAN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE
11-beta,17,21-trihydroxy-5-beta-pregnane-20-dione
11-beta,17,21-trihydroxy-5-beta-pregnane-3,20-dione
11,17,21-trihydroxy-,(5beta,11beta)-pregnane-20-dione
11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE
(5R,8S,9S,10S,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one | [Molecular Formula]
C21H32O5 | [MDL Number]
MFCD00070050 | [MOL File]
1482-50-4.mol | [Molecular Weight]
364.48 |
| Chemical Properties | Back Directory | [Melting point ]
>173°C (dec.) | [Boiling point ]
544.5±50.0 °C(Predicted) | [density ]
1.249±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.50±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. | [Definition]
ChEBI: 5beta-dihydrocortisol is a 17alpha-hydroxy-C21-steroid that is cortisol in which the 4-5 double bond has undergone formal hydrogenation to give the corresponding 5beta- steroid. It is a 21-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, an 11beta-hydroxy steroid, a 3-oxo-5beta-steroid, a primary alpha-hydroxy ketone, a triol, a secondary alcohol, a diketone, a 20-oxo steroid and a tertiary alpha-hydroxy ketone. | [in vivo]
5β-Dihydrocortisol (0.1-1.0%; 18 d) potentiates the action of topically applied Dexamethasone (0.06%) in raising the intraocular pressure (IOP) in young rabbits[3]. |
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Energy Chemical
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