| Identification | Back Directory | [Name]
Dolutegravir O-β-D-Glucuronide Impurity | [CAS]
1485692-21-4 | [Synonyms]
-D-Glucuronide
Dolutegravir O-β-D-Glucuronide
Dolutegravir O-β-D-Glucuronide Impurity | [Molecular Formula]
C26H27F2N3O11 | [MOL File]
1485692-21-4.mol | [Molecular Weight]
595.51 |
| Chemical Properties | Back Directory | [Melting point ]
122 - 124°C | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Methanol (Very Slightly), Water (Slightly, Sonicated) | [form ]
Solid | [color ]
White to Pale Yellow | [Water Solubility ]
Water: slightly, sonicated |
| Hazard Information | Back Directory | [Uses]
Dolutegravir O-β-D-Glucuronide is a metabolite of Dolutegravir (D528800); a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. | [storage]
-20°C |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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