| Identification | Back Directory | [Name]
trans Resveratrol 3-O-β-D-Glucuronide | [CAS]
387372-17-0 | [Synonyms]
Resveratrol-3-Glucuronide
Resveratrol 3-O-Glucuronide
Resveratrol-d4 3-Glucuronide
Resveratrol 3-O-D-Glucuronide
Resveratrol 3-O-B-D-Glucuronide
trans Resveratrol 3-O--D-Glucuronide
trans Resveratrol 3-O-b-D-Glucuronide
trans-Resveratrol-3-O-β-D-Glucuronide
trans-Resveratrol-β-O-β-D-Glucuronide
Resveratrol Impurity 2 (Resveratrol-3-Glucuronide)
3-Hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl
3-Hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl -D-Glucopyranosiduronic Acid
3-Hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl b-D-Glucopyranosiduronic Acid
β-D-Glucopyranosiduronic acid, 3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl | [Molecular Formula]
C20H20O9 | [MOL File]
387372-17-0.mol | [Molecular Weight]
404.37 |
| Chemical Properties | Back Directory | [Melting point ]
>150?C (dec.) | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Beige | [biological source]
synthetic | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. In humans, resveratrol is almost completely conjugated to its glucuronide and sulfate metabolites. trans-Resveratrol-3-O-β-D-glucuronide is a regioisomeric resveratrol metabolite that may be used as a reference standard for accurate determination of the metabolic profile of resveratrol. | [Chemical Properties]
Off-White Solid | [Uses]
A metabolite of trans Resveratrol (R150000). | [Uses]
Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. In humans, resveratrol is almost completely conjugated to its glucuronide and sulfate metabolites. trans-Resveratrol-3-O-β-D-glucuronide is a regioisomeric resveratrol metabolite that may be used as a reference standard for accurate determination of the metabolic profile of resveratrol. | [Definition]
ChEBI: Trans-Resveratrol 3-O-glucuronide is a stilbenoid and a glycoside. | [storage]
Store at -20°C | [References]
[1] G A POTTER. The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1[J]. British Journal of Cancer, 2002, 86 5: 774-778. DOI: 10.1038/sj.bjc.6600197
[2] VIRGINIE AUMONT . Regioselective and Stereospecific Glucuronidation of trans- and cis-Resveratrol in Human[J]. Archives of biochemistry and biophysics, 2001, 393 2: Pages 281-289. DOI: 10.1006/abbi.2001.2496
[3] BARBARA CALAMINI. Pleiotropic mechanisms facilitated by resveratrol and its metabolites.[J]. Biochemical Journal, 2010, 429 2: 273-282. DOI: 10.1042/bj20091857
[4] ELENA POLYCARPOU. Resveratrol 3-O-d-glucuronide and resveratrol 4′-O-d-glucuronide inhibit colon cancer cell growth: Evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest[J]. Molecular Nutrition & Food Research, 2013, 57 10: 1708-1717. DOI: 10.1002/mnfr.201200742
[5] MELLINA S. SIM?ES . Resveratrol biotransformation and actions on the liver metabolism of healthy and arthritic rats[J]. Life sciences, 2022, 310: Article 120991. DOI: 10.1016/j.lfs.2022.120991 |
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