| Identification | Back Directory | [Name]
Quinoline, 6-(3,6-dihydro-6-methyl-2-oxo-2H-1,3,4-thiadiazin-5-yl)-1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroxy-, (-)- | [CAS]
148714-88-9 | [Synonyms]
(-)-Emd 57439
Quinoline, 6-(3,6-dihydro-6-methyl-2-oxo-2H-1,3,4-thiadiazin-5-yl)-1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroxy-, (-)- | [Molecular Formula]
C22H23N3O4S | [MDL Number]
MFCD31560881 | [MOL File]
148714-88-9.mol | [Molecular Weight]
425.5 |
| Hazard Information | Back Directory | [Uses]
EMD 57439 is a selective PDE-III inhibitor. EMD 57439 does not significantly increase c-AMP concentration and has little effect on Ca(50)[1]. | [References]
[1] Kusakari Y,et al. Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca2+ in tetanized rat ventricular myocytes. J Physiol Sci. 2006 Jun;56(3):219-26. DOI:10.2170/physiolsci.RP003706 |
|
|