| Identification | Back Directory | [Name]
SECRETOGRANIN II (154-186) (MOUSE, RAT) | [CAS]
149146-12-3 | [Synonyms]
SECRETONEURIN
SECRETONEURIN (RAT)
SECRETONEURIN (MOUSE, RAT)
SECRETOGRANIN II (154-186) (MOUSE, RAT)
THR-ASN-GLU-ILE-VAL-GLU-GLU-GLN-TYR-THR-PRO-GLN-SER-LEU-ALA-THR-LEU-GLU-SER-VAL-PHE-GLN-GLU-LEU-GLY-LYS-LEU-THR-GLY-PRO-SER-ASN-GLN
H-THR-ASN-GLU-ILE-VAL-GLU-GLU-GLN-TYR-THR-PRO-GLN-SER-LEU-ALA-THR-LEU-GLU-SER-VAL-PHE-GLN-GLU-LEU-GLY-LYS-LEU-THR-GLY-PRO-SER-ASN-GLN-OH | [Molecular Formula]
C28H33NO7 | [MDL Number]
MFCD00274691 | [MOL File]
149146-12-3.mol | [Molecular Weight]
495.564 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [form ]
Solid | [color ]
White to off-white | [Sequence]
Thr-Asn-Glu-Ile-Val-Glu-Glu-Gln-Tyr-Thr-Pro-Gln-Ser-Leu-Ala-Thr-Leu-Glu-Ser-Val-Phe-Gln-Glu-Leu-Gly-Lys-Leu-Thr-Gly-Pro-Ser-Asn-Gln |
| Hazard Information | Back Directory | [Uses]
Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat induces dopamine release in the rat striatum in vivo and in vitro, and it exerts a very strong chemotactic effect on monocytes and eosinophils but not on granulocytes[1]. | [References]
[1] Troger J, et al. Secretoneurin in the peripheral ocular innervation. Invest Ophthalmol Vis Sci. 2005 Feb;46(2):647-54. DOI:10.1167/iovs.04-0425 |
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