| Identification | Back Directory | [Name]
N-methylbiphenyl-2-amine | [CAS]
14925-09-8 | [Synonyms]
2-(Methylamino)biphenyl
N-methylbiphenyl-2-amine
o-(N-Methylamino)biphenyl
N-Methyl-2-biphenylylamine
2-(N-Methylamino)-1,1'-biphenyl
N-Methyl-(1,1'-biphenyl)-2-aMine
[1,1'-Biphenyl]-2-amine, N-methyl-
2-(N-METHYLAMINO)-1,1'-BIPHENYL,MIN.95%
2-(N-Methylamino)-1,1'-biphenyl, min. 95% | [Molecular Formula]
C13H13N | [MDL Number]
MFCD00179576 | [MOL File]
14925-09-8.mol | [Molecular Weight]
183.25 |
| Chemical Properties | Back Directory | [Boiling point ]
330.0±21.0 °C(Predicted) | [density ]
1.052 | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
liquid | [pka]
4.17±0.10(Predicted) | [color ]
pale-yellow | [Sensitive ]
air sensitive | [InChI]
InChI=1S/C13H13N/c1-14-13-10-6-5-9-12(13)11-7-3-2-4-8-11/h2-10,14H,1H3 | [InChIKey]
CARILLOXVAEKID-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=CC=C2)=CC=CC=C1NC |
| Hazard Information | Back Directory | [Synthesis]
N-methylbiphenyl-2-amine synthesis: To a stirred solution of biphenyl-2-amine (0.029 mol) in 2-propanol (125 mL) a solution 37% of formaldehyde in water (0.059 mol) was added and the solution was stirred for 1 h. In another flask, to a suspension of palladium on activated charcoal (0.003 mol) in 2-propanol (125 mL), a solution of ammonium formate (0.29 mol) in water (50 mL) was added. The two solutions were combined and the new suspension was stirred overnight at r.t. and then refluxed for 1 h. After cooling, the suspension was filtered over a Celite pad and the solvent was evaporated. The residue was dissolved in dichloromethane and washed with water. The organic layer was dried over Na2SO4 and evaporated[1]. | [References]
[1] Sozio, P., Marinelli, L., Cacciatore, I., Fontana, A., Türkez, H., Giorgioni, G., Ambrosini, D., Barbato, F., Grumetto, L., Pacella, S., Cataldi, A., Stefano, A. D. (2013). New flurbiprofen derivatives: synthesis, membrane affinity and evaluation of in vitro effect on β-amyloid levels. Molecules, 18 9, 10747–10767. https://doi.org/10.3390/molecules180910747
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Nextpeptide Inc Gold
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www.nextpeptide.com/ |
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SPIRO PHARMA
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www.spiropharma.com.cn |
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