| Identification | Back Directory | [Name]
Efletirizine | [CAS]
150756-35-7 | [Synonyms]
UCB28754
UCB-28754
UCB 28754
Efletirizine
(2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Acetic acid, 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]-
2-[2-[4-[Bis(4-fluorophenyl)methyl]piperazin-1-yl]ethoxy]acetic acid HCl | [Molecular Formula]
C21H24F2N2O3 | [MDL Number]
MFCD00868363 | [MOL File]
150756-35-7.mol | [Molecular Weight]
390.428 |
| Hazard Information | Back Directory | [Uses]
Efletirizine (EFZ) is an orally active antihistamine with high selectivity and affinity to the H1-receptor. Efletirizine can be used for allergic disease research[1]. | [IC 50]
H1 Receptor | [References]
[1] Coe RA, et al. Quantitation of efletirizine in human plasma and urine using automated solid-phase extraction and column-switching high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. 1999 Jul 9;730(2):239-47. DOI:10.1016/s0378-4347(99)00223-6 |
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