ChemicalBook--->CAS DataBase List--->150810-69-8

150810-69-8

150810-69-8 Structure

150810-69-8 Structure
IdentificationBack Directory
[Name]

6-Carboxytetramethylrhodamine succinimidyl ester
[CAS]

150810-69-8
[Synonyms]

6-TAMRA SE
-3H-xanthen-9-yl)
6-TAMRA-NHS ester
-3-(dimethyliminio)
2-(6-(Dimethylamino)
6-TAMRA-SEor6-TAMRA-NHS
-4-(((2,5-dioxopyrrolidin-1-yl)
6-TAMRA SE DISCONTINUED - SEE T305245
6-CARBOXYTETRAMETHYLRHODAMINE, SUCCINIMIDE ESTER
6-CARBOXYTETRAMETHYLRHODAMINE, SUCCINIMIDYL ESTER
6-TAMRA, SE [6-Carboxytetramethylrhodamine, succinimidyl ester
6-Carboxytetramethylrhodamine, succinimidyl ester, single isomer
6-Carboxy-tetramethylrhodamine N-succinimidyl ester, for fluorescence
6-TAMRA, SE [6-Carboxytetramethylrhodamine, succinimidyl ester] *Single isomer*
6-TAMRA, SE [6-Carboxytetramethylrhodamine, succinimidyl ester] *CAS#: 150810-69-8*
[Molecular Formula]

C29H25N3O7
[MDL Number]

MFCD01073639
[MOL File]

150810-69-8.mol
[Molecular Weight]

527.52
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

DMF: soluble
[form ]

Solid
[color ]

Dark purple to black
[Appearance]

Purple solid
[ex/em]

550/576 nm (MeOH/PBS)
[ε(extinction coefficient)]

90000 L⋅mol−1⋅cm−1
[Φ(quantum yield)]

0.1
[Major Application]

diagnostic assay manufacturing
hematology
histology
[InChIKey]

PAOQTZWNYMMSEE-UHFFFAOYSA-N
[SMILES]

C(C1C=CC(=CC=1C1=C2C=CC(=CC2=[O+]C2C=C(C=CC1=2)N(C)C)N(C)C)C(=O)ON1C(CCC1=O)=O)(=O)[O-]
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[F ]

8-10-21
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Description]

TAMRA (tetramethylrhodamine) is a xanthene dye with a fluorescence maximum at 567 nm.


This product is an N-Hydroxysuccinimide (NHS)-ester of TAMRA dye. Pure 6-isomer. TAMRA NHS-ester readily reacts with various amines and is used to generate fluorescently labeled proteins, peptides, antibodies, and other biomolecules.

[Chemical Properties]

Appearance: Purple solid
ex/em: 550/576 nm (MeOH/PBS)
Extinction coefficient (ε): 90000 L??mol??1??cm??1
Quantum yield (Φ): 0.1
[Uses]

Amine-reactive form of 6-Carboxytetramethylrhodamine succinimidyl ester used for labeling of peptides and aminoglycoside antibiotics. It is also most commonly used in automated DNA sequencing.
[Abs/Em Maxima]

541/567 nm
[Fluoresene quantum yield]

0.1
[Extinction Coefficient]

84000
[CF260]

0.34
[CF280]

0.17
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