| Identification | Back Directory | [Name]
1-Methyl-2-tridecylquinolin-4(1H)-one | [CAS]
15266-35-0 | [Synonyms]
Dihydroevocarpine
1-methyl-2-tridecylquinolin-4-one
1-Methyl-2-tridecyl-4(1H)-quinolone
1-Methyl-2-tridecylquinolin-4(1H)-one
4(1H)-Quinolinone, 1-methyl-2-tridecyl- | [Molecular Formula]
C23H35NO | [MDL Number]
MFCD25371972 | [MOL File]
15266-35-0.mol | [Molecular Weight]
341.53 |
| Chemical Properties | Back Directory | [Melting point ]
68-69℃ | [Boiling point ]
447.0±45.0 °C(Predicted) | [density ]
0.964±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
2.52±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from Evodia rutaecarpa (Juss.) Benth. | [Uses]
Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity[1]. | [target]
P-gp | Antifection | MAO | [References]
[1] Zhang S, et al. Targeting of mTORC1/2 by dihydroevocarpine induces cytotoxicity in acute myeloid leukemia.?J Cell Physiol. 2019;234(8):13032-13041. DOI:10.1002/jcp.27974 |
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