| Identification | Back Directory | [Name]
NE 10790 | [CAS]
152831-36-2 | [Synonyms]
3-PEHPC
NE 10790
NE 10790 (3-PEHPC)
FJVYPXVLXQXDHM-UHFFFAOYSA-N
NE 10790 (Synonyms: 3-PEHPC)
3-Pyridinepropanoic acid, α-hydroxy-α-phosphono-
2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoic acid | [Molecular Formula]
C8H10NO6P | [MOL File]
152831-36-2.mol | [Molecular Weight]
247.14 |
| Chemical Properties | Back Directory | [Boiling point ]
583.6±60.0 °C(Predicted) | [density ]
1.724±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
Water:5.0(Max Conc. mg/mL);20.2(Max Conc. mM) | [form ]
Solid | [pka]
1.73±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
H2O: 2mg/mL, clear (Warmed) |
| Hazard Information | Back Directory | [Uses]
3-PEHPC is a phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase and is used in antiosteoporotic drugs. | [Biological Activity]
3-PEHPC (NE 10790)a phosphonocarboxylate analogue of the bisphosphonate risedronateis a potent and selective inhibitor of geranylgeranyl transferase II (GGTase II). |
|
|