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153247-40-6

153247-40-6 Structure

153247-40-6 Structure
IdentificationBack Directory
[Name]

H-LYS-LEU-VAL-PHE-PHE-OH
[CAS]

153247-40-6
[Synonyms]

KLVFF
β-Amyloid (16-20)
LYS-LEU-VAL-PHE-PHE
BETA-AMYLOID (16-20)
H-LYS-LEU-VAL-PHE-PHE-OH
β-Amyloid peptide(16-20)
Amyloid β-Protein (16-20)
AMyloid b-Protein (16-20)
AMYLOID BETA-PROTEIN (16-20)
H-LYS-LEU-VAL-PHE-PHE-OH USP/EP/BP
Amyloid β-Protein (16-20) trifluoroacetate salt
AMYLOID-BETA PROTEIN (16-20), HUMAN, MOUSE, RAT
Amyloid beta-Protein (16-20) trifluoroacetate salt
L-Phenylalanine, L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-
[Molecular Formula]

C35H52N6O6
[MDL Number]

MFCD00798758
[MOL File]

153247-40-6.mol
[Molecular Weight]

652.82
Chemical PropertiesBack Directory
[Boiling point ]

981.7±65.0 °C(Predicted)
[density ]

1.170±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[form ]

Solid
[pka]

3.50±0.10(Predicted)
[color ]

White to off-white
[Sequence]

H-Lys-Leu-Val-Phe-Phe-OH
Hazard InformationBack Directory
[Uses]

β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH2 residues added at N- and C-terminal ends to aid solubility)[1].
[References]

[1] Austen BM, et al. Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide. Biochemistry. 2008 Feb 19;47(7):1984-92. DOI:10.1021/bi701415b
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