| Identification | Back Directory | [Name]
17- Phenyl Trinor Prostaglandin F2α Methyl Amide | [CAS]
155206-01-2 | [Synonyms]
Bimatoprost Impurity 5
Bimatoprost Impurity E
17- Phenyl Trinor Prostaglandin F2α Methyl Amide
17-phenyl trinor Prostaglandin F2.alpha. methyl amide
17- Phenyl Trinor Prostaglandin F2α Methyl Amide (10mg/mL in Ethanol)
(~{Z})-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide
5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-, (5Z)- | [Molecular Formula]
C24H35NO4 | [MOL File]
155206-01-2.mol | [Molecular Weight]
401.54 |
| Chemical Properties | Back Directory | [Boiling point ]
621.5±55.0 °C(Predicted) | [density ]
1.159±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Ethanol | [form ]
Clear Colourless Solution | [pka]
14.25±0.20(Predicted) | [InChIKey]
UWIWNJFBNIMMGY-FDBOBMRISA-N | [SMILES]
C(NC)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCC1=CC=CC=C1 |
| Hazard Information | Back Directory | [Description]
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α.1 The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug.2 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated. | [Uses]
17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is a stable analog of PGF2α and is a potent agonist of for the FP receptor. Analog of Bimatoprost (B386800), an antiglaucoma agent. | [storage]
Store at -20°C |
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