| Identification | Back Directory | [Name]
3-Oxo-5beta-cholanoic Acid | [CAS]
1553-56-6 | [Synonyms]
3-oxocholanicacid
3-KETOCHOLANIC ACID
3-oxolithocholicacid
3-ketolithocholicacid
3-Oxo-5β-cholanic acid
5β-CHOLANIC acid-3-ONE
3-Oxo-5β-cholanoic Acid
3-Oxo-5β-cholanoic Acid
3-Keto-5β-cholanic acid
5β-Cholanic acid-3-one
5-B-CHOLANIC ACID-3-ONE
3-oxocholan-24-oic acid
DEHYDROLITHOCHOLIC ACID
5BETA-CHOLANIC ACID-3-ONE
3-oxo-5beta-cholanic acid
(5-beta)-cholan-24-oicaci
3-Oxo-5beta-cholanoic Acid
3-KETO-5BETA-CHOLANIC ACID
3-Oxo-5β-cholan-24-oic acid
3-oxo-5-beta-cholan-24-oicaci
3-oxo-5-beta-cholan-24-oicacid
3-Keto-5β-cholanic acid, Dehydrolithocholic acid
cell,factor,RAR-related orphan receptor,3 Oxo 5β cholanoic acid,TH17,RORγt,differentiation,acid,bile,Inhibitor,responses,transcription,inhibit,ROR,3Oxo5βcholanoic acid,immune,3-oxoLCA | [Molecular Formula]
C24H38O3 | [MDL Number]
MFCD00046265 | [MOL File]
1553-56-6.mol | [Molecular Weight]
374.56 |
| Chemical Properties | Back Directory | [Melting point ]
140-141 °C | [Boiling point ]
509.3±23.0 °C(Predicted) | [density ]
1.069±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.76±0.10(Predicted) | [color ]
White to Pale Yellow | [CAS DataBase Reference]
1553-56-6 |
| Hazard Information | Back Directory | [Uses]
3-Oxo-5beta-cholanoic Acid is a steroid compound with pharmacological activity. It is a bile acid. Also used in the preparation of lithocholic acid derivatives used as proteasome regulators.
| [Definition]
ChEBI: 3-oxo-5beta-cholanic acid is an oxo-5beta-cholanic acid. It is a conjugate acid of a 3-oxo-5beta-cholanate. | [in vivo]
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (0.3% (w/w); p.o.; for 1 week) significantly reduces the percentage of ileal TH17 cells[1]. | Animal Model: | B6 Jax mice (with a faecal slurry containing SFB)[1] | | Dosage: | 0.3% (w/w) | | Administration: | Gavaged; for 1 week | | Result: | Significantly reduced the percentage of ileal TH17 cells.
|
| [storage]
Store at -20°C |
|
| Company Name: |
TCI Europe
|
| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
| Company Name: |
TCI AMERICA
|
| Tel: |
800-4238616 |
| Website: |
https://www.tcichemicals.com/en/us/index.html |
| Company Name: |
TCI Chemicals
|
| Tel: |
021-67121386, 800-988-0390 |
| Website: |
www.tcichemicals.com |
| Company Name: |
TOSUN PHARM
|
| Tel: |
020-61855200 13326451905 |
| Website: |
www.toref.cn/ |
|