ChemicalBook--->CAS DataBase List--->155584-74-0

155584-74-0

155584-74-0 Structure

155584-74-0 Structure
IdentificationBack Directory
[Name]

VUF 10166
[CAS]

155584-74-0
[Synonyms]

VUF 10166
VUF 10166 USP/EP/BP
2-Chloro-3-(4-Methyl-1-piperazinyl)quinoxaline
2-chloro-3-(4-methylpiperazin-1-yl)quinoxaline
Quinoxaline, 2-chloro-3-(4-methyl-1-piperazinyl)-
[Molecular Formula]

C13H15ClN4
[MDL Number]

MFCD01127814
[MOL File]

155584-74-0.mol
[Molecular Weight]

262.738
Chemical PropertiesBack Directory
[Boiling point ]

389.6±42.0 °C(Predicted)
[density ]

1.279±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

≥26.3 mg/mL in EtOH; insoluble in H2O; ≥38.8 mg/mL in DMSO
[form ]

solid
[pka]

6.55±0.42(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

VUF 10166 is a 5-HT3 receptor antagonist. VUF 10166 exhibits partial agonist activity at 5-HT3A receptors at higher concentrations. VUF 10166 is also histamine H4 receptor antagonist.
[Biological Activity]

vuf10166 is a novel, potent and competitive antagonist for 5-ht3a receptor with ki of 0.04 nm, its affinity at 5-ht3ab receptor is significantly lower.
Spectrum DetailBack Directory
[Spectrum Detail]

VUF 10166(155584-74-0)1HNMR
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