| Identification | Back Directory | [Name]
OSU6162hydrochloride | [CAS]
156907-84-5 | [Synonyms]
PNU-96391
PNU-0096391
OSU6162hydrochloride
(3S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidinehydrochloride
(S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride
(S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine hydrochloride | [Molecular Formula]
C15H23NO2S.ClH | [MDL Number]
MFCD09753276 | [MOL File]
156907-84-5.mol | [Molecular Weight]
317.879 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at +4°C | [solubility ]
H2O: ≥16mg/mL | [form ]
powder | [color ]
white to tan | [Optical Rotation]
[α]/D -5 to -7°, c = 1 in methanol | [Water Solubility ]
H2O: ≥16mg/mL | [InChI]
1S/C15H23NO2S.ClH/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)19(2,17)18;/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3;1H/t14-;/m1./s1 | [InChIKey]
LEMGVHZVBREXAD-PFEQFJNWSA-N | [SMILES]
Cl.CCCN1CCC[C@H](C1)c2cccc(c2)S(C)(=O)=O |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-41 | [Safety Statements ]
26-39 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Uses]
OSU 6162 Hydrochloride is a weak dopamine D2 receptor antagonist. It is a salt analogue of (-)-OSU (O006162). | [Biological Activity]
Dopamine stabilizer that lacks high in vitro affinity for various neuroreceptors (K i values are 447 and 1305 nM for D 2 and D 3 receptors respectively and > 1 μ M for other targets). In vivo, shows high D 2 receptor occupancy and is highly active on dopamine synthesis and turnover. Induces stabilizing effects on psychomotor function in behavioral tests without inducing hypolocomotion or catalepsy. | [storage]
Store at +4°C |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|