ChemicalBook--->CAS DataBase List--->156907-84-5

156907-84-5

156907-84-5 Structure

156907-84-5 Structure
IdentificationBack Directory
[Name]

OSU6162hydrochloride
[CAS]

156907-84-5
[Synonyms]

PNU-96391
PNU-0096391
OSU6162hydrochloride
(3S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidinehydrochloride
(S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride
(S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine hydrochloride
[Molecular Formula]

C15H23NO2S.ClH
[MDL Number]

MFCD09753276
[MOL File]

156907-84-5.mol
[Molecular Weight]

317.879
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

H2O: ≥16mg/mL
[form ]

powder
[color ]

white to tan
[optical activity]

[α]/D -5 to -7°, c = 1 in methanol
[Water Solubility ]

H2O: ≥16mg/mL
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-41
[Safety Statements ]

26-39
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

OSU 6162 Hydrochloride is a weak dopamine D2 receptor antagonist. It is a salt analogue of (-)-OSU (O006162).
[Biological Activity]

Dopamine stabilizer that lacks high in vitro affinity for various neuroreceptors (K i values are 447 and 1305 nM for D 2 and D 3 receptors respectively and > 1 μ M for other targets). In vivo, shows high D 2 receptor occupancy and is highly active on dopamine synthesis and turnover. Induces stabilizing effects on psychomotor function in behavioral tests without inducing hypolocomotion or catalepsy.
[storage]

Store at +4°C
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