| Identification | Back Directory | [Name]
L-Proline, 1-[(2R)-1-oxo-2-[4-[(2-sulfobenzoyl)amino]-1H-imidazol-1-yl]octyl]-4-[4-(phosphonomethyl)phenoxy]-, (4S)- | [CAS]
157187-00-3 | [Synonyms]
LY303336
LY-303336
LY 303336
L-Proline, 1-[(2R)-1-oxo-2-[4-[(2-sulfobenzoyl)amino]-1H-imidazol-1-yl]octyl]-4-[4-(phosphonomethyl)phenoxy]-, (4S)- | [Molecular Formula]
C30H37N4O11PS | [MOL File]
157187-00-3.mol | [Molecular Weight]
692.67 |
| Hazard Information | Back Directory | [Description]
LY303336 is AT1 receptor antagonist. | [Uses]
LY303336 is an antagonist of polysubstituted 4-aminoimidazole AT1 receptor with an IC50 value of 5.2 nM[1]. | [References]
[1] P M Vanderheyden, et al. Inhibition of angiotensin II-induced inositol phosphate production by triacid nonpeptide antagonists in CHO cells expressing human AT1 receptors. Pharm Res. 2000 Dec;17(12):1482-8. DOI:10.1023/a:1007600924033 |
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