ChemicalBook--->CAS DataBase List--->157284-96-3

157284-96-3

157284-96-3 Structure

157284-96-3 Structure
IdentificationBack Directory
[Name]

ANTALARMIN HYDROCHLORIDE
[CAS]

157284-96-3
[Synonyms]

Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-
[Molecular Formula]

C24H34N4
[MDL Number]

MFCD00930939
[MOL File]

157284-96-3.mol
[Molecular Weight]

378.55
Chemical PropertiesBack Directory
[Boiling point ]

437.2±45.0 °C(Predicted)
[density ]

1.05±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: ~24 mg/mL, soluble
[form ]

solid
[pka]

7.10±0.30(Predicted)
[color ]

off-white
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Definition]

ChEBI: Antalarmin is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidin-4-amine which is substituted by methyl groups at positions 2, 5, and 6, by a mesityl group at position 7, and in which the amino substituent at position 4 has been substituted by ethyl and butyl groups. It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors (Ki = 1 nM). It has a role as a corticotropin-releasing factor receptor antagonist. It is a pyrrolopyrimidine and a tertiary amino compound.
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