ChemicalBook--->CAS DataBase List--->160552-55-6

160552-55-6

160552-55-6 Structure

160552-55-6 Structure
IdentificationBack Directory
[Name]

lamivudine sulfoxide
[CAS]

160552-55-6
[Synonyms]

Lamivudine EP IMP G
lamivudine sulfoxide
Lamivudine EP Impurity H
Lamivudine (S)-Sulfoxide
Lamivudine (S)-Sulfoxide Discontinued
Lamivudine Impurity 7(Lamivudine EP Impurity G)
Lamivudine EP Impurity G (Lamivudine (3S)-Sulfoxide)
4-amino-1-((2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
2(1H)-Pyrimidinone, 4-amino-1-[(2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI)
Lamivudine Impurit Ⅳ:4-amino-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
Lamivudine Impurit Ⅳ:4-amino-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
[Molecular Formula]

C8H11N3O4S
[MOL File]

160552-55-6.mol
[Molecular Weight]

245.25
Chemical PropertiesBack Directory
[Melting point ]

>220°C (dec.)
[Boiling point ]

601.7±65.0 °C(Predicted)
[density ]

1.93±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

Solid
[pka]

13.46±0.10(Predicted)
[color ]

White
Hazard InformationBack Directory
[Uses]

Lamivudine (S)-Sulfoxide (Lamivudine EP Impurity G) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
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