| Identification | Back Directory | [Name]
hoi-07 | [CAS]
1606160-40-0 | [Synonyms]
hoi-07
(Z)-3-((E)-4-(benzo[d][1,3]dioxol-5-yl)-2-oxobut-3-enylidene)indolin-2-one
2H-Indol-2-one, 3-[4-(1,3-benzodioxol-5-yl)-2-oxo-3-buten-1-ylidene]-1,3-dihydro- | [Molecular Formula]
C19H13NO4 | [MDL Number]
MFCD26961115 | [MOL File]
1606160-40-0.mol | [Molecular Weight]
319.31 |
| Hazard Information | Back Directory | [Description]
HOI-07 is a specific Aurora B inhibitor. | [Uses]
(E/Z)-HOI-07 is a potent and selective Aurora B inhibitor. HOI-07 has antitumor activity[1]. | [References]
[1] Xie H, et al. Identification of an Aurora kinase inhibitor specific for the Aurora B isoform. Cancer Res. 2013 Jan 15;73(2):716-24. DOI:10.1158/0008-5472.CAN-12-2784 |
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