| Identification | Back Directory | [Name]
1,4-Naphthalenedione, 2-[(3-methylbutyl)amino]- | [CAS]
1607447-79-9 | [Synonyms]
JUN47799
2-(Isopentylamino)naphthalene-1
2-(Isopentylamino)naphthalene-1,4-dione
1,4-Naphthalenedione, 2-[(3-methylbutyl)amino]- | [Molecular Formula]
C15H17NO2 | [MOL File]
1607447-79-9.mol | [Molecular Weight]
243.3 |
| Chemical Properties | Back Directory | [Boiling point ]
381.9±42.0 °C(Predicted) | [density ]
1.13±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml | [form ]
A crystalline solid | [pka]
2.37±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
2-(Isopentylamino)naphthalene-1,4-dione (compound 3d), a Vitamin K (HY-B2172) analogue, shows protection in Pentylenetetrazole (PTZ)-induced seizure model. 2-(Isopentylamino)naphthalene-1,4-dione significantly increases ATP levels in zebrafish as well as HT-22 cells. 2-(Isopentylamino)naphthalene-1,4-dione shows excellent permeability into the brain[1]. | [storage]
Store at -20°C | [References]
[1] Xiaoyang Li, et al. Discovery of the First Vitamin K Analogue as a Potential Treatment of Pharmacoresistant Seizures. J Med Chem. 2020 Jun 11;63(11):5865-5878. DOI:10.1021/acs.jmedchem.0c00168 |
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| Company Name: |
ChemeGen
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18818260767 |
| Website: |
https://www.chemegen.com |
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