ChemicalBook--->CAS DataBase List--->1609281-86-8

1609281-86-8

1609281-86-8 Structure

1609281-86-8 Structure
IdentificationBack Directory
[Name]

AZD3264
[CAS]

1609281-86-8
[Synonyms]

AZD3264
CS-1546
AZD-3264; AZD 3264
3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-[4-(3,5-dimethyl-4-isoxazolyl)-2-[(3S)-3-pyrrolidinyloxy]phenyl]-
[Molecular Formula]

C21H23N5O4S
[MDL Number]

MFCD29472277
[MOL File]

1609281-86-8.mol
[Molecular Weight]

441.5
Chemical PropertiesBack Directory
[Boiling point ]

614.2±55.0 °C(Predicted)
[density ]

1.371±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
[solubility ]

DMF: 30 mg/ml; DMSO: 30 mg/ml
[form ]

A crystalline solid
[pka]

13.16±0.50(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H302-H400-H410
[Precautionary statements ]

P264-P270-P273-P301+P312-P330-P391-P501
Hazard InformationBack Directory
[Uses]

AZD 3264 is a scalable IKK2 Inhibitor .
[in vivo]

AZD3264 is a selective IkB-kinase IKK2 inhibitor, which is currently in preclinical development for the potential treatment of chronic pulmonary obstructive disorder (COPD) and asthma[1].

[IC 50]

IKK2
Spectrum DetailBack Directory
[Spectrum Detail]

AZD3264(1609281-86-8)1HNMR
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