| Identification | Back Directory | [Name]
SEL120-34A | [CAS]
1609522-33-9 | [Synonyms]
SEL120
SEL120-34A
SEL120(SEL120-34，SEL120-34A)
4H-Imidazo[4,5,1-ij]quinoline, 7,8-dibromo-5,6-dihydro-9-methyl-2-(1-piperazinyl)- | [Molecular Formula]
C15H18Br2N4 | [MDL Number]
MFCD31619286 | [MOL File]
1609522-33-9.mol | [Molecular Weight]
414.14 |
| Chemical Properties | Back Directory | [Boiling point ]
557.6±60.0 °C(Predicted) | [density ]
1.92±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
8.60±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
CDK8-IN-2, a CDK8 and/or CDK19 inhibitor. | [in vivo]
SEL120-34A (30, 60 mg/kg, p.o.) inhibits the growth of tumor in mice bearing MV4-11 cancer cells, and also arrests the growth of KG-1-derived tumors at 30 mg/kg via oral administration[1]. | [IC 50]
CDK8/CycC: 4.4 nM (IC50); CDK19/CycC: 10.4 nM (IC50); CDK9/cycT: 1070 nM (IC50) | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
|