| Identification | Back Directory | [Name]
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine | [CAS]
1612191-95-3 | [Synonyms]
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine
9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(1-propyn-1-yl)-3-pyridinyl]- | [Molecular Formula]
C18H16FN5O3 | [MDL Number]
MFCD29915407 | [MOL File]
1612191-95-3.mol | [Molecular Weight]
369.36 |
| Hazard Information | Back Directory | [Uses]
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
|
|