| Identification | Back Directory | [Name]
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine | [CAS]
1612192-01-4 | [Synonyms]
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine
2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-9H-purine
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine
9H-Purine, 2-chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)- | [Molecular Formula]
C14H12ClFN4O3S | [MOL File]
1612192-01-4.mol | [Molecular Weight]
370.78 |
| Hazard Information | Back Directory | [Uses]
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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