ChemicalBook--->CAS DataBase List--->1613200-51-3

1613200-51-3

1613200-51-3 Structure

1613200-51-3 Structure
IdentificationBack Directory
[Name]

ATR inhibitor 1
[CAS]

1613200-51-3
[Synonyms]

Tuvusertib
ATR inhibitor 1
[Molecular Formula]

C16H12F2N8O
[MDL Number]

MFCD32067874
[MOL File]

1613200-51-3.mol
[Molecular Weight]

370.32
Chemical PropertiesBack Directory
[density ]

1.68±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

6.48±0.46(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a Ki value below 1 μΜ[1].
[References]

[1] Nadia AHMAD, et al. Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, the preparation of said compound and different solid forms thereof. WO2015187451A1
[2] Lin Li, et al. Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells DOI:10.1007/s13402-023-00817-6
Spectrum DetailBack Directory
[Spectrum Detail]

ATR inhibitor 1(1613200-51-3)1HNMR
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