| Identification | Back Directory | [Name]
1-METHYL-4-(4-NITROPHENYL)PIPERAZINE | [CAS]
16155-03-6 | [Synonyms]
1-METHYL-4-(4-NITROPHENYL)PIPERAZINE
1-Methyl-4-(4-nitrophenyl)piperizine
1-Methyl-4-(4-nitrophenyl)piperazine95%
Piperazine, 1-Methyl-4-(4-nitrophenyl)-
1-Methyl-4-(4-nitrophenyl)piperazine,97%
1-METHYL-4-(4-NITROPHENYL)PIPERAZINE 95%
1-METHYL-4-(4-NITROPHENYL)PIPERAZIN-1-IUM
1-METHYL-4-(4-NITROPHENYL)PIPERAZINE ISO 9001：2015 REACH | [Molecular Formula]
C11H15N3O2 | [MDL Number]
MFCD00101003 | [MOL File]
16155-03-6.mol | [Molecular Weight]
221.26 |
| Chemical Properties | Back Directory | [Melting point ]
109-111°C | [Boiling point ]
369.5±37.0 °C(Predicted) | [density ]
1.198±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Solid | [pka]
7.41±0.42(Predicted) | [Appearance]
Orange to red Solid | [InChI]
InChI=1S/C11H15N3O2/c1-12-6-8-13(9-7-12)10-2-4-11(5-3-10)14(15)16/h2-5H,6-9H2,1H3 | [InChIKey]
GZNDUKANJZIZOT-UHFFFAOYSA-N | [SMILES]
N1(C)CCN(C2=CC=C([N+]([O-])=O)C=C2)CC1 |
| Hazard Information | Back Directory | [Chemical Properties]
Red solid | [Uses]
1-methyl-4-(4-nitrophenyl)piperazine was a reagent in the preparation of diaminopyrimidines as reversible and irreversible inhibitors of mutant EGFR tyrosine kinases for treatment of non-small-cell lung cancer. It was also used in the prepn. of disubstituted pyrimidine compds. as EGFR or/and ALK inhibitors useful in the treatment of diseases. |
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