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1620692-60-5

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1620692-60-5 Structure

1620692-60-5 Structure

Identification	Back Directory
[Name] KPU-300
[CAS] 1620692-60-5
[Synonyms] KPU-300
[Molecular Formula] C24H17N3O3
[MOL File] 1620692-60-5.mol
[Molecular Weight] 395.41

Chemical Properties	Back Directory
[Boiling point ] 774.3±60.0 °C(Predicted)
[density ] 1.324±0.06 g/cm3(Predicted)
[pka] 10.85±0.20(Predicted)

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[Description] KPU-300 is a potent and selective antimicrotubule agent. KPU-300 exhibited a potent cytotoxicity with an IC50 value of 7.0 nM against HT-29 cells, by strongly binding to tubulin (K d = 1.3 μM) and inducing microtubule depolymerization.
[Uses] KPU-300 (compound 6b) is a tubulin inhibitor. KPU-300 has potent cytotoxicity with an IC50 value of 7.0 nM against HT-29 cells[1].
[References] [1] Yoshiki Hayashi, et al. Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure. ACS Med Chem Lett. 2014 Jul 23;5(10):1094-8. DOI:10.1021/ml5001883

1620692-60-5 suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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