| Identification | More | [Name]
3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE | [CAS]
16290-26-9 | [Synonyms]
3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE
4-(AMINOMETHYL)CATECHOL HYDROBROMIDE
DHBA
DHBA HYDROBROMIDE
4-(aminomethyl)pyrocatechol hydrobromide
3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE, 9 8%
4-(Aminomethyl)catechol hydrobromide, DHBA hydrobromide
3,4-Dihydroxybenzylamine·hydrogen bromide
4-(Aminomethyl)pyrocatechol·hydrobrominate | [EINECS(EC#)]
240-382-8 | [Molecular Formula]
C7H10BrNO2 | [MDL Number]
MFCD00012859 | [Molecular Weight]
220.06 | [MOL File]
16290-26-9.mol |
| Chemical Properties | Back Directory | [Appearance]
light beige crystalline powder | [Melting point ]
184-186 °C(lit.) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Very Slightly) | [form ]
Crystalline Powder | [color ]
Light beige | [Sensitive ]
Hygroscopic | [BRN ]
4002646 | [CAS DataBase Reference]
16290-26-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
10 | [HS Code ]
29222900 |
| Hazard Information | Back Directory | [Chemical Properties]
light beige crystalline powder | [Uses]
4-(Aminomethyl)benzene-1,2-diol hydrobromide is a useful reactant for the synthesis of capsaicin soft drugs. which are used to target the transient receptor potential vanilloid 1 channel (TRPV1). | [in vivo]
3,4-Dihydroxybenzylamine hydrobromide (intraperitoneal injection; 1000 mg/kg; 7 days) has the least toxic effect in non-tumor-bearing B6D2F1 mice,and mice is tolerated at this dose[3].
3,4-Dihydroxybenzylamine hydrobromide (intraperitoneal injection; 200-800 mg/kg; 21 days) has different effects at different doses, the median life-span are 17, 24.5, 26, 29 and 25 days for 0 mg/kg, 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg, respectively[3]. | Animal Model: | C57BL/6 mice with B6D2F1 cells[3] | | Dosage: | 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg | | Administration: | Intraperitoneal injection | | Result: | Exhibited increased life-span of 44%,46%, 70% and 50% for 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg, respectively. |
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