Hazard Information | Back Directory | [Description]
CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM. CDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The tmax is 0.25 h by PO. The mean values of Cmax are 9940 μg/L, 12740 μg/L by IV and PO respectively. The values of AUC are 9378, 25952 by IV and PO respectively[1]. | [storage]
Store at -20°C | [References]
[1]. Han X, et al. Discovery of potent and selective CDK8 inhibitors through FBDD approach. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4488-4492. |
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Company Name: |
cjbscvictory
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Tel: |
13348960310 13348960310 |
Website: |
http://www.weikeqi-biotech.com/ |
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