| Identification | Back Directory | [Name]
Benzenepropanamine, N-methyl-γ-[2-(methylthio)phenoxy]-, (γR)- | [CAS]
163059-33-4 | [Synonyms]
LY368975
LY-368975
LY 368975
(R)-Thionisoxetine
Benzenepropanamine, N-methyl-γ-[2-(methylthio)phenoxy]-, (γR)- | [Molecular Formula]
C17H21NOS | [MDL Number]
MFCD06198718 | [MOL File]
163059-33-4.mol | [Molecular Weight]
287.42 |
| Hazard Information | Back Directory | [Uses]
(R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED50 of 0.21 mg/kg. (R)-Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence[1]. | [References]
[1] Gehlert DR, et al. (R)-thionisoxetine, a potent and selective inhibitor of central and peripheral norepinephrine uptake. Life Sci. 1995;56(22):1915-20. DOI:10.1016/0024-3205(95)00166-4 |
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