| Identification | More | [Name]
1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE | [CAS]
1631-28-3 | [Synonyms]
1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE 1-P-TOLYL-PYRROLE-2,5-DIONE AKOS B006714 AKOS MSC-0013 ART-CHEM-BB B006714 ASISCHEM S97813 N-(4-METHYLPHENYL)MALEIMIDE N-(P-TOLYL)MALEIMIDE IT 510 Maleimide, N-p-Tolyl- N-(para-Tolyl)-maleimide N-(p-Methylphenyl)maleimide N-4-Tolylmaleimide n-p-tolyl-maleimid p-Tolylmaleimide 1-(4-Methylphenyl)-3-pyrroline-2,5-dione 1-p-Tolyl-3-pyrroline-2,5-dione | [Molecular Formula]
C11H9NO2 | [MDL Number]
MFCD00022581 | [Molecular Weight]
187.19 | [MOL File]
1631-28-3.mol |
| Hazard Information | Back Directory | [Uses]
p-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis[1]. | [References]
[1] Machado KE, et al. Apoptotic events induced by maleimides on human acute leukemia cell lines. Chem Res Toxicol. 2013 Dec 16;26(12):1904-16. DOI:10.1021/tx400284r |
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