| Identification | Back Directory | [Name]
RATJADONE A | [CAS]
163564-92-9 | [Synonyms]
RATJADON
RATJADONE
RATJADONE A
2H-Pyran-2-one, 5,6-dihydro-6-[(1E,3Z,5R,7E,9E,11R)-11-hydroxy-3,5,7-trimethyl-11-[(2S,4R,5S,6S)-tetrahydro-4-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-1,3,7,9-undecatetraen-1-yl]-, (6R)- | [Molecular Formula]
C28H40O5 | [MDL Number]
MFCD32705544 | [MOL File]
163564-92-9.mol | [Molecular Weight]
456.61 |
| Hazard Information | Back Directory | [Uses]
Ratjadone A, Synthetic is a cell-permeable polyketide that inhibits cell proliferation. | [Biological Activity]
Cell permeable: yes''Primary Target
nuclear export of LR-NES''Product does not compete with ATP.''Reversible: no''Target IC50: ≤ 1 ng/ml for inhibiting proliferation and inducing cell cycle arrest at G1 phase |
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