ChemicalBook--->CAS DataBase List--->163768-50-1

163768-50-1

163768-50-1 Structure

163768-50-1 Structure
IdentificationBack Directory
[Name]

Auristatin F
[CAS]

163768-50-1
[Synonyms]

CS-1370
Auristatin F
Auristantin F
Auristatin F (AF)
Auristatin F TFA Salt
L-Phenylalanine, N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-
N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide
[Molecular Formula]

C40H67N5O8
[MDL Number]

MFCD25976745
[MOL File]

163768-50-1.mol
[Molecular Weight]

746
Chemical PropertiesBack Directory
[Melting point ]

>140°C (dec.)
[Boiling point ]

894.4±65.0 °C(Predicted)
[density ]

1.112±0.06 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[pka]

3.56±0.10(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Description]

Auristatin F is a cytotoxin that works as a microtubule inhibitor and vascular damaging agent.
[Uses]

Auristatin F is an antimitotic auristatin derivative that has been shown as a potent antitumor agent.
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