Identification | Back Directory | [Name]
Longiferone B | [CAS]
1639810-67-5 | [Synonyms]
Longiferone B 5(1H)-Azulenone, 2,3,3a,4,8,8a-hexahydro-6,8a-dimethyl-3-(1-methylethenyl)-, (3R,3aS,8aR)-rel- | [Molecular Formula]
C15H22O | [MDL Number]
MFCD30723029 | [MOL File]
1639810-67-5.mol | [Molecular Weight]
218.33 |
Hazard Information | Back Directory | [Uses]
Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression[1]. | [IC 50]
iNOS; COX-2 | [References]
[1] Sudsai T, et al. Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes. J Ethnopharmacol. 2014 Jun 11;154(2):453-61. DOI:10.1016/j.jep.2014.04.034 |
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