ChemicalBook--->CAS DataBase List--->1639810-67-5

1639810-67-5

1639810-67-5 Structure

1639810-67-5 Structure
IdentificationBack Directory
[Name]

Longiferone B
[CAS]

1639810-67-5
[Synonyms]

Longiferone B
5(1H)-Azulenone, 2,3,3a,4,8,8a-hexahydro-6,8a-dimethyl-3-(1-methylethenyl)-, (3R,3aS,8aR)-rel-
[Molecular Formula]

C15H22O
[MDL Number]

MFCD30723029
[MOL File]

1639810-67-5.mol
[Molecular Weight]

218.33
Chemical PropertiesBack Directory
[Boiling point ]

309.5±22.0 °C(Predicted)
[density ]

0.963±0.06 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression[1].
[IC 50]

iNOS; COX-2
[References]

[1] Sudsai T, et al. Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes. J Ethnopharmacol. 2014 Jun 11;154(2):453-61. DOI:10.1016/j.jep.2014.04.034
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